Ubrelvy: Facts About the New Migraine Medication for Adults


Here’s a piece of wonderful news for all American migraineurs: The U.S. Food and Drug Administration has recently approved Ubrelvy, a new prescription medication that can treat acute migraine attacks with or without aura in adults. Furthermore, the drug will be available for sale in the United States in the first quarter of 2020. 

What is a Migraine?

Migraine is a neurological disorder that brings about moderate to severe headaches. A throbbing or pulsating pain often afflicts one side of the head. It may come with nausea and vomiting, as well as aura and sensitivity to sounds, lights, and smells. 

The FDA’s approval of Ubrelvy provides a new relief option for 39 million American migraine patients. Those adults who suffer from episodes of migraines with or without aura can benefit from it.

An aura is any visual, sensory, or motor disturbances, such as seeing flickering lights or zigzag lines. It can also display as pins and needles feeling, numbness, or auditory hallucinations. 

Important Facts You Need to Know About Ubrelvy

1. It can relieve migraines during an attack.

Ubrelvy (ubrogepant) tablets can offer immediate treatment of migraines with or without aura in adults. There are only two ways to relieve migraines— through prevention of an attack or relief of its symptoms during an episode. Ubrelvy works for the speedy treatment of symptoms during a migraine episode. However, it remains unknown if it can treat migraines in children.

2. Ubrevly is the first approved migraine drug in its class. 

Ubrelvy is the first oral pill of a class of drugs called calcitonin gene-related peptide (CGRP) inhibitors approved for the acute care of migraines. In short, it can be taken orally and can stop a migraine attack in progress. As the first oral gepant, Ubrelvy can help migraineurs alleviate the debilitating head pain and other symptoms of migraines. It can be an alternative to triptans. 

3. Two trials have proved its effectiveness. 

According to the FDA, two randomized, double-blind, placebo-controlled trials showed pieces of evidence of the efficacy of Ubrelvy. In the said studies, a total of 1,439 adult migraineurs participated. All patients had migraines with and without aura and took permitted doses of Ubrelvy during migraine attacks. At the end of both studies, more patients experienced pain freedom and reversal of migraine symptoms two hours after taking Ubrelvy compared to those who received a placebo. 

4. Ubrelvy has side effects.

While it can stop migraines, the FDA warned that it has possible adverse side effects in patients such as nausea, tiredness, sleepiness, and dry mouth. The agency also said there are several contraindications for Ubrelvy. Patients who are already taking a strong CYP3A4 inhibitor cannot take Ubrelvy. The suggested dose of Ubrelvy is 50 mg or 100 mg. If another dose is essential, it should be taken at least 2 hours after the initial dose. The maximum dose migraine patients can receive is 200 mg in 24 hours. 

5. It is not recommended for some people.

Migraine patients should inform their doctor about all their existing health conditions before taking Ubrelvy as it can be risky for the health, especially to people who:

  • have kidney problems
  • have liver issues
  • are pregnant or planning to become pregnant – it is unknown if Ubrelvy can harm unborn babies.
  • are breastfeeding or planning to breastfeed – it is unknown if Ubrelvy passes into the breast milk.

Also, share your doctor all the medications, vitamins, and herbal supplements you take before taking Ubrelvy. 

Upper Cervical Care Natural Migraine Solution

For those migraineurs who prefer natural care, there is a natural alternative that has been delivering a solution for many migraine patients. Upper cervical chiropractic has helped many patients keep their migraine attacks at bay.

Often the onset of migraines has some link to a misalignment in the topmost bones of the neck, the C1 and C2 vertebrae.

Undesirable Results of Upper Cervical Misalignments

A misalignment of either the C1 or C2 vertebra of the upper cervical spine can result in the following:  

  • Restricted blood flow between the body and brain
  • Inaccurate sending of signals between the brain and body, which can cause in an overall malfunction of the nervous system 
  • Limited circulation of cerebrospinal fluid, which can disrupt the supply of nutrients in the body

All of these can bring symptoms of migraines. A form of natural therapy, upper cervical chiropractic care adjusts the misaligned bones to bring back their proper alignment. Upper cervical chiropractors use only gentle and low force to do so.

Once corrections become successful, proper blood circulation can return in the brain and migraines may improve or disappear altogether.

Like Ubrelvy medication, several case studies have backed the effectiveness of upper cervical chiropractic. Many patients reported a reduction in the frequency and severity of their migraine headaches after receiving this unique type of care. Some even said their migraine attacks never happen again. The advantage is that upper cervical chiropractic has none of the side effects of Ubrelvy. 

Utilize the search functionality on our website to find an upper cervical chiropractor in your area.  Most of them offer a no-obligation consultation.

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The content and materials provided in this web site are for informational and educational purposes only and are not intended to supplement or comprise a medical diagnosis or other professional opinion, or to be used in lieu of a consultation with a physician or competent health care professional for medical diagnosis and/or treatment. All content and materials including research papers, case studies and testimonials summarizing patients' responses to care are intended for educational purposes only and do not imply a guarantee of benefit. Individual results may vary, depending upon several factors including age of the patient, severity of the condition, severity of the spinal injury, and duration of time the condition has been present.